Thousands of protesters took to the streets of several U.S. cities and college campuses Wednesday to express their disdain for president-elect Donald Trump.

NEW YORK CITY

A massive gathering of protesters descended upon Trump Tower in midtown Manhattan Wednesday night, marching from Union Square.

Protesters chanted, "My body, my choice," "Not my president," and "Hey, hey, ho, ho, Donald Trump has got to go."

At Union Square, hundreds chanted "He's Not My President" and carried signs that read "Defeat Fascism." Another group of protesters gathered at Columbus Circle near Trump International Hotel & Tower.

At least 15 people were arrested during Wednesday night's demonstrations, according to WABC. Sources also tell WABC that at least 10,000 people took part in NYC demonstrations.

CHICAGO

In Chicago, hundreds of protesters marched through the city's downtown and gathered outside the city's Trump Tower to express their anger that Trump was elected.

"You saw all of the hate was coming with him, and you were just hoping that that would never come to fruition, and it has," anti-Trump protester Will Rossi told Chicago's ABC7.

Some protesters also gathered outside the newly-opened Trump Hotel.

Students at American University protested on campus.

LOS ANGELES

Hundreds of people took to the streets of downtown Los Angeles to express their disgust with president-elect Trump.

Many protesters gathered at City Hall, where they burned a pinata of Trump. Protesters also descended upon the 101 freeway in downtown Los Angeles, forcing its shutdown.